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Limited Foxp3(+) Regulatory T Cells Response During Acute Trypanosoma cruzi Infection Is Required to Allow the Emergence of Robust Parasite-Specific CD8(+) T Cell Immunity

While it is now acknowledged that CD4(+) T cells expressing CD25 and Foxp3 (Treg cells) regulate immune responses and, consequently, influence the pathogenesis of infectious diseases, the regulatory response mediated by Treg cells upon infection by Trypanosoma cruzi was still poorly characterized. I...

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Publicado en:Front Immunol
Main Authors: Araujo Furlan, Cintia L., Tosello Boari, Jimena, Rodriguez, Constanza, Canale, Fernando P., Fiocca Vernengo, Facundo, Boccardo, Santiago, Beccaria, Cristian G., Adoue, Véronique, Joffre, Olivier, Gruppi, Adriana, Montes, Carolina L., Acosta Rodriguez, Eva V.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6230662/
https://ncbi.nlm.nih.gov/pubmed/30455700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02555
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