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T cell Allorecognition Pathways in Solid Organ Transplantation

Transplantation is unusual in that T cells can recognize alloantigen by at least two distinct pathways: as intact MHC alloantigen on the surface of donor cells via the direct pathway; and as self-restricted processed alloantigen via the indirect pathway. Direct pathway responses are viewed as strong...

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Pubblicato in:Front Immunol
Autori principali: Siu, Jacqueline H. Y., Surendrakumar, Veena, Richards, James A., Pettigrew, Gavin J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6230624/
https://ncbi.nlm.nih.gov/pubmed/30455697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02548
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