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A ROLE FOR NRF2 ACTIVATION IN DELAYED AGING: EVIDENCE FROM BENCH TO BEDSIDE
Nrf2 induces the transcription of genes that favor cell survival including mitochondrial biogenesis, phase II antioxidant and detoxification, and anti-inflammation. Our studies in vitro indicate that Nrf2 activation protects cells against oxidant-induced cell death. In vivo, we have shown that Nrf2...
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| izdano v: | Innov Aging |
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| Glavni avtor: | |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2018
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6229612/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igy023.673 |
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