Tau-induced focal neurotoxicity and network disruption related to apathy in Alzheimer’s disease

OBJECTIVE: Apathy is a common neuropsychological symptom in Alzheimer’s disease (AD), and previous studies demonstrated that neuronal loss and network disruption in some brain regions play pivotal roles in the pathogenesis of apathy. However, contributions of tau and amyloid-β (Aβ) depositions, path...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Neurol Neurosurg Psychiatry
Prif Awduron: Kitamura, Soichiro, Shimada, Hitoshi, Niwa, Fumitoshi, Endo, Hironobu, Shinotoh, Hitoshi, Takahata, Keisuke, Kubota, Manabu, Takado, Yuhei, Hirano, Shigeki, Kimura, Yasuyuki, Zhang, Ming-Rong, Kuwabara, Satoshi, Suhara, Tetsuya, Higuchi, Makoto
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BMJ Publishing Group 2018
Pynciau:
Neuropsychiatry
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6227800/
https://ncbi.nlm.nih.gov/pubmed/29884723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jnnp-2018-317970
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