Tau-induced focal neurotoxicity and network disruption related to apathy in Alzheimer’s disease

OBJECTIVE: Apathy is a common neuropsychological symptom in Alzheimer’s disease (AD), and previous studies demonstrated that neuronal loss and network disruption in some brain regions play pivotal roles in the pathogenesis of apathy. However, contributions of tau and amyloid-β (Aβ) depositions, path...

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Опубликовано в: :J Neurol Neurosurg Psychiatry
Главные авторы: Kitamura, Soichiro, Shimada, Hitoshi, Niwa, Fumitoshi, Endo, Hironobu, Shinotoh, Hitoshi, Takahata, Keisuke, Kubota, Manabu, Takado, Yuhei, Hirano, Shigeki, Kimura, Yasuyuki, Zhang, Ming-Rong, Kuwabara, Satoshi, Suhara, Tetsuya, Higuchi, Makoto
Формат: Artigo
Язык:Inglês
Опубликовано: BMJ Publishing Group 2018
Предметы:
Neuropsychiatry
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6227800/
https://ncbi.nlm.nih.gov/pubmed/29884723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jnnp-2018-317970
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