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HYDROGEN SULFIDE AMELIORATES KIDNEY CHANGES IN AGING AND DIABETES
Hydrogen sulfide (H2S) is constitutively synthesized in the kidney. Kidney H2S generation is reduced in aging mice and is associated with oxidative stress, reduction in Nrf2, decrease in AMPK activity and activation of insulin receptor (IR)/ IRS-2-Akt-mTORC1 signaling axis in association with increa...
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| Pubblicato in: | Innov Aging |
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| Autore principale: | |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6227307/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igy023.1280 |
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