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Embryonic Stem Cells Derived Kidney Organoids as Faithful Models to Target Programmed Nephrogenesis

The kidney is a complex organ that is comprised of thousands of nephrons developing through reciprocal inductive interactions between metanephric mesenchyme (MM) and ureteric bud (UB). The MM undergoes mesenchymal to epithelial transition (MET) in response to the signaling from the UB. The secreted...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Tan, Zenglai, Shan, Jingdong, Rak-Raszewska, Aleksandra, Vainio, Seppo J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6226521/
https://ncbi.nlm.nih.gov/pubmed/30413738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-34995-3
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