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Transcriptome-wide identification of transient RNA G-quadruplexes in human cells

Guanine-rich RNA sequences can fold into four-stranded structures, termed G-quadruplexes (G4-RNAs), whose biological roles are poorly understood, and in vivo existence is debated. To profile biologically relevant G4-RNA in the human transcriptome, we report here on G4RP-seq, which combines G4-RNA-sp...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Yang, Sunny Y., Lejault, Pauline, Chevrier, Sandy, Boidot, Romain, Robertson, A. Gordon, Wong, Judy M. Y., Monchaud, David
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6226477/
https://ncbi.nlm.nih.gov/pubmed/30413703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07224-8
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