Structure analysis and antiviral activity of CW-33 analogues against Japanese encephalitis virus

Japanese encephalitis virus (JEV) is a member of neurotropic flaviviruses transmitted by mosquito bites, causing severe central nervous system disorders. Current JEV genotype III vaccines have a low protection against genotype I isolates in the risk zone. The lead compound CW-33, ethyl 2-(3′,5′-dime...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Lien, Jin-Cherng, Wang, Ching-Ying, Lai, Hsueh–Chou, Lu, Chien-Yi, Lin, Yu-Fong, Gao, Ging-Yan, Chen, Kuan-Chung, Huang, An-Cheng, Huang, Su-Hua, Lin, Cheng-Wen
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6226475/
https://ncbi.nlm.nih.gov/pubmed/30413749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-34932-4
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