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Perineuronal nets decrease membrane capacitance of peritumoral fast spiking interneurons in a model of epilepsy

Brain tumor patients commonly present with epileptic seizures. We show that tumor-associated seizures are the consequence of impaired GABAergic inhibition due to an overall loss of peritumoral fast spiking interneurons (FSNs) concomitant with a significantly reduced firing rate of those that remain....

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nat Commun
Egile Nagusiak: Tewari, Bhanu P., Chaunsali, Lata, Campbell, Susan L., Patel, Dipan C., Goode, Adam E., Sontheimer, Harald
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6226462/
https://ncbi.nlm.nih.gov/pubmed/30413686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07113-0
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