Targeting SHIP-1 in Myeloid Cells Enhances Trained Immunity and Boosts Response to Infection

β-Glucan-induced trained immunity in myeloid cells leads to long-term protection against secondary infections. Although previous studies have characterized this phenomenon, strategies to boost trained immunity remain undefined. We found that β-glucan-trained macrophages from mice with a myeloid-spec...

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Опубликовано в: :Cell Rep
Главные авторы: Saz-Leal, Paula, del Fresno, Carlos, Brandi, Paola, Martínez-Cano, Sarai, Dungan, Otto M., Chisholm, John D., Kerr, William G., Sancho, David
Формат: Artigo
Язык:Inglês
Опубликовано: Cell Press 2018
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6226423/
https://ncbi.nlm.nih.gov/pubmed/30380404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.09.092
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