AlphaE Integrin Expression Is Increased in the Ileum Relative to the Colon and Unaffected by Inflammation

BACKGROUND: Recent findings suggest that αE expression is enriched on effector T cells and that intestinal αE(+) T cells have increased expression of inflammatory cytokines. αE integrin expression is a potential predictive biomarker for response to etrolizumab, a monoclonal antibody against β7 integ...

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Dades bibliogràfiques
Publicat a:J Crohns Colitis
Autors principals: Ichikawa, Ryan, Lamb, Christopher A, Eastham-Anderson, Jeff, Scherl, Alexis, Raffals, Laura, Faubion, William A, Bennett, Miriam R, Long, Anna K, Mansfield, John C, Kirby, John A, Keir, Mary E
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2018
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6225976/
https://ncbi.nlm.nih.gov/pubmed/29912405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ecco-jcc/jjy084
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