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EZH2 contributes to 5-FU resistance in gastric cancer by epigenetically suppressing FBXO32 expression

BACKGROUND: Increasing evidence suggests the involvement of enhancer of zeste homologue 2 (EZH2) in chemoresistance of cancer treatment. Nevertheless, its function and molecular mechanisms in gastric cancer (GC) chemoresistance are still not well elucidated. MATERIALS AND METHODS: In the present stu...

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Bibliographische Detailangaben
Veröffentlicht in:Onco Targets Ther
Hauptverfasser: Wang, Chenyu, Li, Xingwang, Zhang, Junjie, Ge, Zheng, Chen, Hejin, Hu, Junhong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6225849/
https://ncbi.nlm.nih.gov/pubmed/30464532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S180131
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