Three-tiered score for Ki-67 and p16(ink4a) improves accuracy and reproducibility of grading CIN lesions

AIMS: To investigate the accuracy and reproducibility of a scoring system for cervical intraepithelial neoplasia (CIN1–3) based on immunohistochemical (IHC) biomarkers Ki-67 and p16(ink4a). METHODS: 115 cervical tissue specimens were reviewed by three expert gynaecopathologists and graded according...

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Detalhes bibliográficos
Publicado no:J Clin Pathol
Main Authors: van Zummeren, Marjolein, Leeman, Annemiek, Kremer, Wieke W, Bleeker, Maaike C G, Jenkins, David, van de Sandt, Miekel, Heideman, Daniëlle A M, Steenbergen, Renske, Snijders, Peter J F, Quint, Wim G V, Berkhof, Johannes, Meijer, Chris J L M
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2018
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6225805/
https://ncbi.nlm.nih.gov/pubmed/30012698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jclinpath-2018-205271
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