Metformin induces apoptosis in mesenchymal stromal cells and dampens their therapeutic efficacy in infarcted myocardium

BACKGROUND: Cardiovascular complications, especially myocardial infarctions (MIs), are the leading mortality cause in diabetic patients. The transplantation of stem cells into damaged hearts has had considerable success as a treatment for MI, although whether antidiabetic drugs affect the therapeuti...

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Dettagli Bibliografici
Pubblicato in:Stem Cell Res Ther
Autori principali: He, Xiao, Yao, Meng-Wei, Zhu, Ming, Liang, Dong-Lan, Guo, Wei, Yang, Yi, Zhao, Rong-Seng, Ren, Ting-Ting, Ao, Xiang, Wang, Wei, Zeng, Chun-Yu, Liang, Hua-Ping, Jiang, Dong-po, Yu, Jian, Xu, Xiang
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6225675/
https://ncbi.nlm.nih.gov/pubmed/30409193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-018-1057-0
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