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Synthesis and Antiproliferative Activity of New Cyclodiprenyl Phenols against Select Cancer Cell Lines

Six new cyclodiprenyl phenols were synthesized by direct coupling of perillyl alcohol and the appropriate phenol. Their structures were established by IR, HRMS and mainly NMR. Three human cancer cell lines—breast (MCF-7), prostate (PC-3) and colon (HT-29)—were used in antiproliferative assays, with...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Said, Bastián, Montenegro, Iván, Valenzuela, Manuel, Olguín, Yusser, Caro, Nelson, Werner, Enrique, Godoy, Patricio, Villena, Joan, Madrid, Alejandro
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6225466/
https://ncbi.nlm.nih.gov/pubmed/30213053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23092323
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