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Development and characterization of sorafenib-loaded lipid nanocapsules for the treatment of glioblastoma

Anticancer agents that target both tumor cells and angiogenesis are of potential interest for glioblastoma (GB) therapy. One such agent is sorafenib (SFN), a tyrosine kinase inhibitor. However, poor aqueous solubility and undesirable side effects limit its clinical application, including local treat...

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Detalhes bibliográficos
Publicado no:Drug Deliv
Main Authors: Clavreul, Anne, Roger, Emilie, Pourbaghi-Masouleh, Milad, Lemaire, Laurent, Tétaud, Clément, Menei, Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6225440/
https://ncbi.nlm.nih.gov/pubmed/30338715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2018.1507061
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