Simultaneous Determination of Aesculin, Aesculetin, Fraxetin, Fraxin and Polydatin in Beagle Dog Plasma by UPLC-ESI-MS/MS and Its Application in a Pharmacokinetic Study after Oral Administration Extracts of Ledum palustre L.

A rapid, simple and sensitive ultra-performance liquid chromatography-electrospray-ionization-tandem mass spectrometry (UPLC-ESI-MS/MS) method was developed and validated for the simultaneous determination of aesculin, aesculetin, fraxetin, fraxin and polydatin in beagle dog plasma for the first tim...

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Publicat a:Molecules
Autors principals: Wang, Zhibin, Zhu, Wenbo, Liu, Hua, Wu, Gaosong, Song, Mengmeng, Yang, Bingyou, Yang, Deqiang, Wang, Qiuhong, Kuang, Haixue
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6225292/
https://ncbi.nlm.nih.gov/pubmed/30205426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23092285
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