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Novel Group of AChE Reactivators—Synthesis, In Vitro Reactivation and Molecular Docking Study

The acetylcholinesterase (AChE) reactivators (e.g., obidoxime, asoxime) became an essential part of organophosphorus (OP) poisoning treatment, together with atropine and diazepam. They are referred to as a causal treatment of OP poisoning, because they are able to split the OP moiety from AChE activ...

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Bibliografske podrobnosti
izdano v:Molecules
Main Authors: Malinak, David, Nepovimova, Eugenie, Jun, Daniel, Musilek, Kamil, Kuca, Kamil
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6225275/
https://ncbi.nlm.nih.gov/pubmed/30205495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23092291
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