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Novel Group of AChE Reactivators—Synthesis, In Vitro Reactivation and Molecular Docking Study

The acetylcholinesterase (AChE) reactivators (e.g., obidoxime, asoxime) became an essential part of organophosphorus (OP) poisoning treatment, together with atropine and diazepam. They are referred to as a causal treatment of OP poisoning, because they are able to split the OP moiety from AChE activ...

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Vydáno v:Molecules
Hlavní autoři: Malinak, David, Nepovimova, Eugenie, Jun, Daniel, Musilek, Kamil, Kuca, Kamil
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6225275/
https://ncbi.nlm.nih.gov/pubmed/30205495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23092291
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