A complete Leishmania donovani reference genome identifies novel genetic variations associated with virulence

Leishmania donovani is responsible for visceral leishmaniasis, a neglected and lethal parasitic disease with limited treatment options and no vaccine. The study of L. donovani has been hindered by the lack of a high-quality reference genome and this can impact experimental outcomes including the ide...

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Udgivet i:Sci Rep
Main Authors: Lypaczewski, Patrick, Hoshizaki, Johanna, Zhang, Wen-Wei, McCall, Laura-Isobel, Torcivia-Rodriguez, John, Simonyan, Vahan, Kaur, Amanpreet, Dewar, Ken, Matlashewski, Greg
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6224596/
https://ncbi.nlm.nih.gov/pubmed/30409989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-34812-x
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