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Resolution of inflammation-induced depression requires T lymphocytes and endogenous brain interleukin-10 signaling

In humans, depression is often associated with low-grade inflammation, activation of the tryptophan/kynurenine pathway, and mild lymphopenia. Preclinical research confirms that inflammation induces depression-like behavior through activation of the tryptophan/kynurenine pathway. However, the mechani...

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Bibliografiske detaljer
Udgivet i:Neuropsychopharmacology
Main Authors: Laumet, Geoffroy, Edralin, Jules Daniel, Chiang, Angie Chi-An, Dantzer, Robert, Heijnen, Cobi J., Kavelaars, Annemieke
Format: Artigo
Sprog:Inglês
Udgivet: Springer International Publishing 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6224384/
https://ncbi.nlm.nih.gov/pubmed/30054585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-018-0154-1
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