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Epigenetic ageing is distinct from senescence-mediated ageing and is not prevented by telomerase expression

The paramount role of senescent cells in ageing has prompted suggestions that re-expression of telomerase may prevent ageing; a proposition that is predicated on the assumption that senescent cells are the sole cause of ageing. Recently, several DNA methylation-based age estimators (epigenetic clock...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Aging (Albany NY)
Hauptverfasser: Kabacik, Sylwia, Horvath, Steve, Cohen, Howard, Raj, Kenneth
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6224244/
https://ncbi.nlm.nih.gov/pubmed/30332397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101588
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