The mitomiR/Bcl-2 axis affects mitochondrial function and autophagic vacuole formation in senescent endothelial cells

During senescence, cells undergo distinctive biochemical and morphological changes and become dysfunctional. MiRNAs are involved in the senescence process and specific miRNAs can localize to mitochondria (mitomiRs). We hypothesized that part of the typical alterations of senescence may depends on mi...

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Bibliographische Detailangaben
Veröffentlicht in:Aging (Albany NY)
Hauptverfasser: Giuliani, Angelica, Cirilli, Ilenia, Prattichizzo, Francesco, Mensà, Emanuela, Fulgenzi, Gianluca, Sabbatinelli, Jacopo, Graciotti, Laura, Olivieri, Fabiola, Procopio, Antonio Domenico, Tiano, Luca, Rippo, Maria Rita
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals 2018
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6224225/
https://ncbi.nlm.nih.gov/pubmed/30348904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101591
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