The mitomiR/Bcl-2 axis affects mitochondrial function and autophagic vacuole formation in senescent endothelial cells

During senescence, cells undergo distinctive biochemical and morphological changes and become dysfunctional. MiRNAs are involved in the senescence process and specific miRNAs can localize to mitochondria (mitomiRs). We hypothesized that part of the typical alterations of senescence may depends on mi...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Aging (Albany NY)
Main Authors: Giuliani, Angelica, Cirilli, Ilenia, Prattichizzo, Francesco, Mensà, Emanuela, Fulgenzi, Gianluca, Sabbatinelli, Jacopo, Graciotti, Laura, Olivieri, Fabiola, Procopio, Antonio Domenico, Tiano, Luca, Rippo, Maria Rita
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals 2018
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6224225/
https://ncbi.nlm.nih.gov/pubmed/30348904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101591
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