Age-related epigenome-wide DNA methylation and hydroxymethylation in longitudinal mouse blood

DNA methylation at cytosine-phosphate-guanine (CpG) dinucleotides changes as a function of age in humans and animal models, a process that may contribute to chronic disease development. Recent studies have investigated the role of an oxidized form of DNA methylation – 5-hydroxymethylcytosine (5hmC)...

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Detalhes bibliográficos
Publicado no:Epigenetics
Main Authors: Kochmanski, Joseph, Marchlewicz, Elizabeth H., Cavalcante, Raymond G., Sartor, Maureen A., Dolinoy, Dana C.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6224215/
https://ncbi.nlm.nih.gov/pubmed/30079798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2018.1507198
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