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Simultaneous determination of tryptophan and its 31 catabolites in mouse tissues by polarity switching UHPLC-SRM-MS

Tryptophan (TRP) and its catabolites have attracted a lot of attention because of their clinical significance to human health. Recently, microbiome-gut-brain axis was found to have links to many diseases based on the imbalance of TRP catabolism. By using ultra-high performance liquid chromatography...

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Bibliographic Details
Published in:Anal Chim Acta
Main Authors: Chen, Guan-yuan, Zhong, Wei, Zhou, Zhanxiang, Zhang, Qibin
Format: Artigo
Language:Inglês
Published: 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6224157/
https://ncbi.nlm.nih.gov/pubmed/30292294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.aca.2018.02.026
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