Generation of Cas9 transgenic zebrafish and their application in establishing an ERV-deficient animal model

OBJECTIVES: To investigate the effect of endogenous Cas9 on genome editing efficiency in transgenic zebrafish. RESULTS: Here we have constructed a transgenic zebrafish strain that can be screened by pigment deficiency. Compared with the traditional CRISPR injection method, the transgenic zebrafish c...

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Bibliographic Details
Published in:Biotechnol Lett
Main Authors: Yang, Zhe, Chen, Shihao, Xue, Songlei, Li, Xinxiu, Sun, Zhen, Yang, Yu, Hu, Xuming, Geng, Tuoyu, Cui, Hengmi
Format: Artigo
Language:Inglês
Published: Springer Netherlands 2018
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Original Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6223727/
https://ncbi.nlm.nih.gov/pubmed/30244429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10529-018-2605-5
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