MicroRNA-645 targets urokinase plasminogen activator and decreases the invasive growth of MDA-MB-231 triple-negative breast cancer cells

BACKGROUND: Urokinase plasminogen activator (uPA) promotes the in vivo invasive growth of HCC cells by cleaving and activating matrix metalloproteinases (MMPs) to induce the destruction of the extracellular matrix of triple-negative breast cancer (TNBC) cells. The identification of microRNAs that ta...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Meng, Du, Lei, Ming, Han, Yaxuan, Zhao, Dongli, Zhang, Xiaozhi, Yang, Yunyi, Liu, Rui
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6223385/
https://ncbi.nlm.nih.gov/pubmed/30464522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S187221
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