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Simulation-based benchmarking of isoform quantification in single-cell RNA-seq

Single-cell RNA-seq has the potential to facilitate isoform quantification as the confounding factor of a mixed population of cells is eliminated. However, best practice for using existing quantification methods has not been established. We carry out a benchmark for five popular isoform quantificati...

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Bibliografske podrobnosti
izdano v:Genome Biol
Main Authors: Westoby, Jennifer, Herrera, Marcela Sjöberg, Ferguson-Smith, Anne C., Hemberg, Martin
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6223048/
https://ncbi.nlm.nih.gov/pubmed/30404663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-018-1571-5
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