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2′-O-Methyl-8-methylguanosine as a Z-Form RNA Stabilizer for Structural and Functional Study of Z-RNA

In contrast to Z-DNA that was stabilized and well-studied for its structure by chemical approaches, the stabilization and structural study of Z-RNA remains a challenge. In this study, we developed a Z-form RNA stabilizer m(8)Gm, and demonstrated that incorporation of m(8)Gm into RNA can markedly sta...

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Detalles Bibliográficos
Publicado en:Molecules
Main Authors: Balasubramaniyam, Thananjeyan, Ishizuka, Takumi, Xiao, Chao-Da, Bao, Hong-Liang, Xu, Yan
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6222775/
https://ncbi.nlm.nih.gov/pubmed/30304782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23102572
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