Application of Neurokinin-1 Receptor in Targeted Strategies for Glioma Treatment. Part I: Synthesis and Evaluation of Substance P Fragments Labeled with (99m)Tc and (177)Lu as Potential Receptor Radiopharmaceuticals

Gliomas, particularly WHO grade IV glioblastoma multiforme, are one of the most common and aggressive primary tumors of the central nervous system. The neuropeptide, substance P (SP), is the physiological ligand of the neurokinin-1 (NK-1) receptor that is consistently overexpressed in glioblastoma c...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Molecules
Asıl Yazarlar: Majkowska-Pilip, Agnieszka, Koźmiński, Przemysław, Wawrzynowska, Anna, Budlewski, Tadeusz, Kostkiewicz, Bogusław, Gniazdowska, Ewa
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6222600/
https://ncbi.nlm.nih.gov/pubmed/30301182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23102542
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