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Evaluation of Amino-Functional Polyester Dendrimers Based on Bis-MPA as Nonviral Vectors for siRNA Delivery

Herein, we present the first evaluation of cationic dendrimers based on 2,2-bis(methylol)propionic acid (bis-MPA) as nonviral vectors for transfection of short interfering RNA (siRNA) in cell cultures. The study encompassed dendrimers of generation one to four (G1–G4), modified to bear 6–48 amino en...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Stenström, Patrik, Manzanares, Dario, Zhang, Yuning, Ceña, Valentin, Malkoch, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6222295/
https://ncbi.nlm.nih.gov/pubmed/30110914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23082028
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