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The long noncoding RNA GAS8-AS1 suppresses hepatocarcinogenesis by epigenetically activating the tumor suppressor GAS8

Long noncoding RNAs (lncRNAs) are vital players in cancers, including hepatocellular carcinoma (HCC). We previously identified an lncRNA, GAS8-AS1, that is located in intron 2 of GAS8. However, its involvement in HCC is still largely unknown. In this study, we report that both GAS8-AS1 and its host...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Autores principales: Pan, Wenting, Zhang, Nasha, Liu, Wenjuan, Liu, Jibing, Zhou, Liqing, Liu, Yang, Yang, Ming
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2018
Materias:
RNA
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6222094/
https://ncbi.nlm.nih.gov/pubmed/30228180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.003055
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