Non-apoptotic Fas (CD95) Signaling on T Cells Regulates the Resolution of Th2-Mediated Inflammation

Fas (CD95/APO-1) and its ligand (FasL/CD95L) promote the resolution of type 2 lung inflammation and eosinophilia. We previously found that Fas-deficiency on T cells, but not eosinophils, delayed resolution of inflammation. However, Fas can signal both cell death and have a positive signaling functio...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Williams, Jesse W., Ferreira, Caroline M., Blaine, Kelly M., Rayon, Crystal, Velázquez, Francisco, Tong, Jiankun, Peter, Marcus E., Sperling, Anne I.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6221963/
https://ncbi.nlm.nih.gov/pubmed/30443253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02521
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