Lung Dendritic Cells Drive Natural Killer Cytotoxicity in Chronic Obstructive Pulmonary Disease via IL-15Rα

Rationale: Lung natural killer cells (NKs) kill a greater percentage of autologous lung parenchymal cells in chronic obstructive pulmonary disease (COPD) than in nonobstructed smokers. To become cytotoxic, NKs require priming, typically by dendritic cells (DCs), but whether priming occurs in the lun...

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Detalhes bibliográficos
Publicado no:Am J Respir Crit Care Med
Main Authors: Finch, Donna K., Stolberg, Valerie R., Ferguson, John, Alikaj, Henrih, Kady, Mohamed R., Richmond, Bradley W., Polosukhin, Vasiliy V., Blackwell, Timothy S., McCloskey, Lisa, Curtis, Jeffrey L., Freeman, Christine M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6221577/
https://ncbi.nlm.nih.gov/pubmed/29676596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201712-2513OC
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