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The metabolic and molecular mechanisms of hyperammonaemia‐ and hyperethanolaemia‐induced protein catabolism in skeletal muscle cells

Hyperammonaemia and hyperethanolaemia are thought to be driving factors behind skeletal muscle myopathy in liver disease, that is, cirrhosis. Despite this, the singular and combined impacts of ethanol‐ and ammonia‐induced protein catabolism are poorly defined. As such, we aimed to dissect out the ef...

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Detalhes bibliográficos
Publicado no:J Cell Physiol
Main Authors: Crossland, Hannah, Smith, Kenneth, Atherton, Philip J., Wilkinson, Daniel J.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6220958/
https://ncbi.nlm.nih.gov/pubmed/30144060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.26881
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