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The metabolic and molecular mechanisms of hyperammonaemia‐ and hyperethanolaemia‐induced protein catabolism in skeletal muscle cells

Hyperammonaemia and hyperethanolaemia are thought to be driving factors behind skeletal muscle myopathy in liver disease, that is, cirrhosis. Despite this, the singular and combined impacts of ethanol‐ and ammonia‐induced protein catabolism are poorly defined. As such, we aimed to dissect out the ef...

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Publicado en:J Cell Physiol
Autores principales: Crossland, Hannah, Smith, Kenneth, Atherton, Philip J., Wilkinson, Daniel J.
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6220958/
https://ncbi.nlm.nih.gov/pubmed/30144060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.26881
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