Genetic dissection of the miR-200–Zeb1 axis reveals its importance in tumor differentiation and invasion

The epithelial-to-mesenchymal transition (EMT) is an important mechanism for cancer progression and metastasis. Numerous in vitro and tumor-profiling studies point to the miR-200–Zeb1 axis as crucial in regulating this process, yet in vivo studies involving its regulation within a physiological cont...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Title, Alexandra C., Hong, Sue-Jean, Pires, Nuno D., Hasenöhrl, Lynn, Godbersen, Svenja, Stokar-Regenscheit, Nadine, Bartel, David P., Stoffel, Markus
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6220299/
https://ncbi.nlm.nih.gov/pubmed/30405106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07130-z
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