Predictive value of ERCC1, ERCC2, ERCC4, and glutathione S-Transferase Pi expression for the efficacy and safety of FOLFIRINOX in patients with unresectable pancreatic cancer

The platinum-based chemotherapy regimen FOLFIRINOX (leucovorin, fluorouracil, irinotecan, and oxaliplatin) is currently used as a standard treatment for patients with unresectable pancreatic cancer. FOLFIRINOX is associated with severe toxicities, including neutropenia, febrile neutropenia, and anor...

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Vydáno v:Am J Cancer Res
Hlavní autoři: Tezuka, Shun, Ueno, Makoto, Kobayashi, Satoshi, Morimoto, Manabu, Ohkawa, Shinichi, Hirotani, Akane, Tozuka, Yuichiro, Moriya, Satoshi, Nakamura, Yoshiyasu, Miyagi, Yohei, Sugimori, Makoto, Maeda, Shin
Médium: Artigo
Jazyk:Inglês
Vydáno: e-Century Publishing Corporation 2018
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6220150/
https://ncbi.nlm.nih.gov/pubmed/30416859
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