Novel nano-drug combination therapeutic regimen demonstrates significant efficacy in the transgenic mouse model of pancreatic ductal adenocarcinoma

The current work studied the chemopreventive efficacy of orally administered chitosan coated solid-lipid nanoparticle (c-SLN) encapsulated aspirin (ASP), curcumin (CUR) and free sulforaphane (SFN), ACS-cSLN, in the LSL-Kras (G12D/+); Pdx-1 (Cre/+) transgenic mouse model of pancreatic ductal adenocar...

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Vydáno v:Am J Cancer Res
Hlavní autoři: Thakkar, Arvind, Desai, Preshita, Chenreddy, Sushma, Modi, Jalpa, Thio, Astrid, Khamas, Wael, Ann, David, Wang, Jeffrey, Prabhu, Sunil
Médium: Artigo
Jazyk:Inglês
Vydáno: e-Century Publishing Corporation 2018
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6220149/
https://ncbi.nlm.nih.gov/pubmed/30416852
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