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Mismatch repair-based stratification for immune checkpoint blockade therapy

Mismatch repair (MMR) plays a key role in maintaining genomic stability. Mismatch repair deficiency (MMR-D) causes a molecular feature of microsatellite instability (MSI) and contributes to the development of human cancers and genetic diseases with cancer predisposition such as Lynch syndrome. Recen...

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Detalhes bibliográficos
Publicado no:Am J Cancer Res
Main Authors: Zhang, Lihong, Peng, Yang, Peng, Guang
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6220134/
https://ncbi.nlm.nih.gov/pubmed/30416850
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