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RNA splicing in the transition from B cells to antibody secreting cells; the influences of ELL2, snRNA, and ER stress

In the transition from B cells to antibody secreting cells (ASCs) many genes are induced, like ELL2, Irf4, Prdm1, Xbp1, while other mRNAs do not change in abundance. Nonetheless using splicing array technology and mouse splenic B cells +/− LPS we found that induced and “un-induced” genes can show la...

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Pubblicato in:J Immunol
Autori principali: Nelson, Ashley M., Carew, Nolan T., Smith, Sage M., Milcarek, Christine
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6219926/
https://ncbi.nlm.nih.gov/pubmed/30297340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1800557
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