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Lipin-1 regulates Bnip3–mediated mitophagy in glycolytic muscle

Autophagy of mitochondria (mitophagy) is essential for maintaining muscle mass and healthy skeletal muscle. Patients with heritable phosphatidic acid phosphatase lipin-1–null mutations present with severe rhabdomyolysis and muscle atrophy in glycolytic muscle fibers, which are accompanied with mitoc...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Alshudukhi, Abdullah A., Zhu, Jing, Huang, Dengtong, Jama, Abdulrahman, Smith, Jeffrey D., Wang, Qing Jun, Esser, Karyn A., Ren, Hongmei
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6219840/
https://ncbi.nlm.nih.gov/pubmed/29939786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201800374
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