Oxidant sensor cation channel TRPM2 regulates neutrophil extracellular trap formation and protects against pneumoseptic bacterial infection

Neutrophil extracellular trap (NET) formation constitutes an important extracellular antimicrobial function of neutrophils that plays a protective role in bacterial pneumonia. Formation of reactive oxygen species (ROS) such as highly diffusible hydrogen peroxide (H(2)O(2)) is a hallmark of oxidative...

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Bibliografische gegevens
Gepubliceerd in:FASEB J
Hoofdauteurs: Tripathi, Jitendra Kumar, Sharma, Atul, Sukumaran, Pramod, Sun, Yuyang, Mishra, Bibhuti Bhusan, Singh, Brij Bhan, Sharma, Jyotika
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Federation of American Societies for Experimental Biology 2018
Onderwerpen:
Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6219830/
https://ncbi.nlm.nih.gov/pubmed/29906250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201800605
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