Extracellular microvesicle microRNAs as predictive biomarkers for targeted therapy in metastastic cutaneous malignant melanoma

BACKGROUND: Mitogen activated-protein kinase pathway inhibitors (MAPKis) improve treatment outcome in patients with disseminated BRAFV600 mutant cutaneous malignant melanoma (CMM) but responses are of limited duration due to emerging resistance. Although extensive research in mechanisms of resistanc...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Svedman, Fernanda Costa, Lohcharoenkal, Warangkana, Bottai, Matteo, Brage, Suzanne Egyhazi, Sonkoly, Enikö, Hansson, Johan, Pivarcsi, Andor, Eriksson, Hanna
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6219796/
https://ncbi.nlm.nih.gov/pubmed/30399176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0206942
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