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GATA4 as a novel regulator involved in the development of the neural crest and craniofacial skeleton via Barx1

The role of GATA-binding protein 4 (GATA4) in neural crest cells (NCCs) is poorly defined. Here we showed that mouse NCCs lacking GATA4 exhibited developmental defects in craniofacial bone, teeth, and heart. The defects likely occurred due to decreased cell proliferation at the developmental stage....

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Guo, Shuyu, Zhang, Yuxin, Zhou, Tingting, Wang, Dongyue, Weng, Yajuan, Chen, Qi, Ma, Junqing, Li, Yi-ping, Wang, Lin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6219484/
https://ncbi.nlm.nih.gov/pubmed/29523871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-018-0083-x
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