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Nuclear transport inhibition in acute myeloid leukemia: recent advances and future perspectives

Selective inhibitors of nuclear export (SINE) are emerging as a potentially efficacious therapeutic strategy for overcoming resistance to conventional chemotherapy for acute myeloid leukemia. SINE specifically block the protein Exportin 1, also known as chromosomal region maintenance 1, leading to n...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Int J Hematol Oncol
Hauptverfasser: Talati, Chetasi, Sweet, Kendra L
Format: Artigo
Sprache:Inglês
Veröffentlicht: Future Medicine Ltd 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6219429/
https://ncbi.nlm.nih.gov/pubmed/30405902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/ijh-2018-0001
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