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Nuclear transport inhibition in acute myeloid leukemia: recent advances and future perspectives

Selective inhibitors of nuclear export (SINE) are emerging as a potentially efficacious therapeutic strategy for overcoming resistance to conventional chemotherapy for acute myeloid leukemia. SINE specifically block the protein Exportin 1, also known as chromosomal region maintenance 1, leading to n...

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Detalhes bibliográficos
Publicado no:Int J Hematol Oncol
Main Authors: Talati, Chetasi, Sweet, Kendra L
Formato: Artigo
Idioma:Inglês
Publicado em: Future Medicine Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6219429/
https://ncbi.nlm.nih.gov/pubmed/30405902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/ijh-2018-0001
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