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Computation of a Theoretical Membrane Phase Diagram, and the Role of Phase in Lipid Raft-Mediated Protein Organization

Lipid phase heterogeneity in the plasma membrane is thought to be crucial for many aspects of cell signaling, but the physical basis of participating membrane domains such as “lipid rafts” remains controversial. Here we consider a lattice model yielding a phase diagram that includes several states p...

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Detalhes bibliográficos
Publicado no:J Phys Chem B
Main Authors: Mitra, Eshan D., Whitehead, Samuel C., Holowka, David, Baird, Barbara, Sethna, James P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6219384/
https://ncbi.nlm.nih.gov/pubmed/29432021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.7b10695
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