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Decrease in Intracellular Perforin Levels and IFN-γ Production in Human CD8(+) T Cell Line following Long-Term Exposure to Asbestos Fibers

Although the tumorigenicity of asbestos, which is thought to cause mesothelioma, has been clarified, its effect on antitumor immunity requires further investigation. We previously reported a decrease in the percentage of perforin(+) cells of stimulated CD8(+) lymphocytes derived from patients with m...

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Detalhes bibliográficos
Publicado no:J Immunol Res
Main Authors: Kumagai-Takei, Naoko, Nishimura, Yasumitsu, Matsuzaki, Hidenori, Lee, Suni, Yoshitome, Kei, Otsuki, Takemi
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6218727/
https://ncbi.nlm.nih.gov/pubmed/30426024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/4391731
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