Highly Potent 1H-1,2,3-Triazole-Tethered Isatin-Metronidazole Conjugates Against Anaerobic Foodborne, Waterborne, and Sexually-Transmitted Protozoal Parasites

Parasitic infections like amebiasis, trichomoniasis, and giardiasis are major health threats in tropical and subtropical regions of the world. Metronidazole (MTZ) is the current drug of choice for amebiasis, giardiasis, and trichomoniasis but it has several adverse effects and potential resistance i...

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Detalhes bibliográficos
Publicado no:Front Cell Infect Microbiol
Main Authors: Kumar, Sumit, Bains, Trpta, Won Kim, Ashley Sae, Tam, Christina, Kim, Jong, Cheng, Luisa W., Land, Kirkwood M., Debnath, Anjan, Kumar, Vipan
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Cellular and Infection Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6218680/
https://ncbi.nlm.nih.gov/pubmed/30425970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2018.00380
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