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Adenosinergic Signaling Alters Natural Killer Cell Functional Responses
Adenosine is a potent immunosuppressive purine metabolite contributing to the pathogenesis of solid tumors. Extracellular adenosine signals on tumor-infiltrating NK cells to inhibit their proliferation, maturation, and cytotoxic function. Cytokine priming imparts upon NK cells distinct activation st...
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| Publicado no: | Front Immunol |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6218627/ https://ncbi.nlm.nih.gov/pubmed/30425720 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02533 |
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