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The glucocorticoid-Angptl4-ceramide axis induces insulin resistance through PP2A and PKCζ
Chronic glucocorticoid exposure is associated with the development of insulin resistance. We showed that glucocorticoid-induced insulin resistance was attenuated upon ablation of Angptl4, a glucocorticoid target gene encoding the secreted protein angiopoietin-like 4, which mediates glucocorticoid-in...
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| Foilsithe in: | Sci Signal |
|---|---|
| Main Authors: | , , , , , , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
2017
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6218395/ https://ncbi.nlm.nih.gov/pubmed/28743803 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aai7905 |
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