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Data-driven, voxel-based analysis of brain PET images: Application of PCA and LASSO methods to visualize and quantify patterns of neurodegeneration

Spatial patterns of radiotracer binding in positron emission tomography (PET) images may convey information related to the disease topology. However, this information is not captured by the standard PET image analysis that quantifies the mean radiotracer uptake within a region of interest (ROI). On...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Klyuzhin, Ivan S., Fu, Jessie F., Hong, Andy, Sacheli, Matthew, Shenkov, Nikolay, Matarazzo, Michele, Rahmim, Arman, Stoessl, A. Jon, Sossi, Vesna
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6218048/
https://ncbi.nlm.nih.gov/pubmed/30395576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0206607
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